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Article

Clinically significant findings of high-risk mutations in human SLC29A4 gene associated with diabetes mellitus type 2 in Pakistani population.

Journal of biomolecular structure & dynamics - 1 Jan 2022

Moeez Sadaf, Khalid Sumbul, Shaeen Sania, Khalid Madiha, Zia Asima, Gul Asma, Niazi Rauf, Khalid Zoya

Abstract excerpt

This study conducted an in-depth analysis combining computational and experimental verifications of the deleterious missense mutations associated with the SLC29A4 protein. The functional annotation of the non-synonymous single nucleotide polymorphism (nsSNPs), followed by structure-function analysis, revealed 13 single nucleotide polymorphisms (SNP) as the most damaging. Among these, six mutants P429T/S, L144S,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34551672
DOI: 10.1080/07391102.2021.1975561

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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