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Article

A rare missense variant in Bruton's tyrosine kinase is associated with bipolar disorder accompanied by psychosis.

Psychiatric genetics - 1 Sept 2026

Kanwal Ambreen, Cheema Husnain Arshad, Jabbar Nauman, Iftikhar Amina, Pardo Jose V, Naz Sadaf

Abstract excerpt

INTRODUCTION: Bipolar disorder is a mental disorder associated with extreme mood shifts. Psychosis (hallucinations, delusions, and thought disorder) can also co-occur in some patients. Although highly heritable, the genetic etiology of bipolar disorder remains unclear. METHODS: We visited outpatient departments of mental hospitals and recruited all members of a consanguineous family in which multiple siblings had...

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Share to Agammaglobulinaemia Tyrosine Kinase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 42308110
DOI: 10.1097/YPG.0000000000000422

Genes

BTK

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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