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Article

Exonic DNA sequencing of ERBB4 in bipolar disorder.

PloS one - 1 Jan 2011

Goes Fernando S, Rongione Michael, Chen Yun-Ching, Karchin Rachel, Elhaik Eran, Potash James B

Abstract excerpt

The Neuregulin-ErbB4 pathway plays a crucial role in brain development and constitutes one of the most biologically plausible signaling pathways implicated in schizophrenia and, to a lesser extent, in bipolar disorder (BP). However, recent genome-wide association analyses have not provided evidence for common variation in NRG1 or ERBB4 influencing schizophrenia or bipolar disorder susceptibility. In this study,...

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Share to Bipolar Disorder
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ERBB4 gene

Share to Genetic Predisposition to Disease

Share to Polymorphism, Single Nucleotide

Share to Receptor, ErbB-4

Share to Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 21637803
DOI: 10.1371/journal.pone.0020242
PMCID: PMC3102700

Genes

ERBB4
NRG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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