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Article

Fibrocytes with different phenotypes are recruited in chronic obstructive pulmonary disease.

Scientific reports - 15 Jun 2026

Yao Xiujuan, Chen Qinglin, Liu Xiaofang, Zhang Luo

Abstract excerpt

Previous studies showed that fibrocytes are increased in the circulation and in the airway walls of chronic obstructive pulmonary disease (COPD) patients. However, it is unclear whether fibrocytes express different phenotypes. The aim of the study was to further evaluate the recruitment and phenotypic characteristics of fibrocytes in patients and murine models with COPD. By using flow cytometry analysis, blood...

Read the complete abstract on PubMed

Topics

Pulmonary Disease, Chronic Obstructive
Humans
Animals
Female
Phenotype
Male
Aged

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Mice

Middle Aged

Receptors, CXCR4

Disease Models, Animal

Fibroblasts

Case-Control Studies

Source

Open in PubMed Open full text

Identifiers

PMID: 42297864
DOI: 10.1038/s41598-026-56766-1
PMCID: PMC13530249

Genes

CXCL12
CXCR4
TSLP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

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