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Article

Impact of ClockΔ19 mutation on neural recording performance and neural inflammatory responses.

Biomaterials - 1 Dec 2026

Dhawan Vaishnavi, Narayanan Sharada, Thompson Cort, Shi Delin, Patel Yugma, McClung Colleen A, Cui Xinyan Tracy

Abstract excerpt

Chronically implanted neural electrodes for neural recording, stimulation, and chemical sensing are essential tools in studying and treating neurological disorders. However, their performances are limited by implant-induced inflammation, causing a loss in signal quality over time. Because disease states can alter inflammatory processes, it is critical to characterize the tissue response to neural implants within...

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PMID: 42275847
DOI: 10.1016/j.biomaterials.2026.124369

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