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Article

Deciphering the Pleiotropic Role of ARID1a and RIF1 in Endometrioid Ovarian Cancer.

Cells - 4 Jun 2026

Kordowitzki Pawel, Velho Renata Voltolini, Bock Sandra, Sehouli Jalid, Mechsner Sylvia

Abstract excerpt

BACKGROUND: Given the challenges in early detection and diagnosis, understanding the molecular underpinnings of endometrioid ovarian cancer (EOC) is crucial for improving patient outcomes. This multi-level study provides a new perspective on EOC, focusing on the expression of ARID1a (BAF250a) and RIF1. METHODS: This study evaluates patient cohorts with EOC through semi-quantitative immunohistochemical staining of...

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Share to BRCA1 Protein
Share to Carcinoma, Endometrioid
Share to DNA-Binding Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Mutation

Share to Ovarian Neoplasms

Share to Telomere-Binding Proteins

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Source

Open in PubMed Open full text

Identifiers

PMID: 42274628
DOI: 10.3390/cells15111036
PMCID: PMC13257199

Genes

BRCA1
LAMB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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