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Article

Ovarian Clear Cell Carcinoma Sub-Typing by ARID1A Expression.

Yonsei medical journal - 1 Jan 2017

Choi Jae Yoon, Han Hyun Ho, Kim Young Tae, Lee Joo Hyun, Kim Baek Gil, Kang Suki, Cho Nam Hoon

Abstract excerpt

PURPOSE: Loss of AT-rich DNA-interacting domain 1A (ARID1A) has been identified as a driving mutation of ovarian clear cell carcinoma (O-CCC), a triple-negative ovarian cancer that is intermediary between serous and endometrioid subtypes, in regards to molecular and clinical behaviors. However, about half of O-CCCs still express BAF250a, the protein encoded by ARID1A. Herein, we aimed to identify signatures of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27873496
DOI: 10.3349/ymj.2017.58.1.59
PMCID: PMC5122653

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