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Article

Immune Pressure From Plasma From Immunocompromised and Healthy Individuals Drives Differential SARS-CoV-2 Evolution and Escape Mutation Emergence.

Journal of medical virology - 1 Jun 2026

Fu Jolene Yin Ling, Lim Soo Kun, Jalalonmuhali Maisarah, Bador Maria Kahar, Sam I-Ching, Chan Yoke Fun

Abstract excerpt

Immunocompromised individuals with prolonged SARS-CoV-2 infections are recognized reservoirs for viral evolution and the emergence of immune escape variants. We investigated intra-host evolutionary dynamics of SARS-CoV-2 under distinct immune pressures exerted by plasma from kidney transplant recipients (KTRs). Wild-type (WT) SARS-CoV-2 (B.6.6) and Omicron subvariants (BA.5.2 and XBB.1.5.57) were serially...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42272263
DOI: 10.1002/jmv.71016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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