Article
Mitochondrial transfer reveals an organellar layer of cancer ecology.
Trends in cancer - 1 Aug 2026
Okwan-Duodu Derick, Li Bo, Engleman Edgar
Abstract excerpt
Tumors are ecological systems shaped by continuous exchange with surrounding cells. The transfer of functional mitochondria, which reprograms malignant behavior, introduces a distinct layer to this ecology. Cancer evolution may proceed not solely through mutation and selection but also through the horizontal assimilation of organellar traits acquired from neighboring cells.
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