Article
Acute pain transfusion reaction in a patient with thalassemia: In-depth characterization of short- and long-term phenotypes.
Transfusion - 1 Jul 2026
Tzafa Georgia, Delicou Sophia, Barla Ioanna, Theocharaki Konstantina, Kondi Aggeliki, Velentzas Athanassios D, Simantiris Nikolaos, Stylianaki Elli-Anna, Mpekoulis George, Pavlou Efthymia, Vassilaki Niki, Kostopoulos Ioannis V, Xydaki Aikaterini, Nomikou Efrosyni, Aggeli Ioanna-Katerina, Thomaidis Nikolaos, Gikas Evangelos, Samiotaki Martina, Zoidakis Jerome, Politis Constantina, Antonelou Marianna H
Abstract excerpt
BACKGROUND: Acute pain transfusion reaction (APTR) is a rare, under-recognized condition of unknown etiology. It can cause significant distress in recipients, necessitating symptomatic management and, occasionally, hospitalization. STUDY DESIGN AND METHODS: Here, we present an APTR event in an adult subject with transfusion-dependent thalassemia (TDT). Patient and returned red blood cell (RBC) unit samples from...
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