Extracellular Vesicles in Beta-Thalassemia: Phenotype-Specific Profiles and Potential Clinical Associations.

Abstract excerpt

Βeta-thalassemia is one of the most common genetic disorders worldwide, characterized by ineffective erythropoiesis (IE), which leads to a wide spectrum of heterogeneous disease-related complications. Extracellular vesicles (EVs) have emerged as having important roles in β-thalassemia complications; however, phenotype-specific differences and their relevance to clinical outcomes remain incompletely defined. This...

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