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Article

Identification of potential drug targets for delirium from genetic insights: A Mendelian randomization study.

Brain research bulletin - 1 May 2026

Geng Yan-Na, Dong Xu, Liu Yuan, Dong Yan

Abstract excerpt

Delirium, a prevalent acute cerebral disorder, currently lacks effective pharmacological interventions despite its substantial clinical impact. Leveraging genetic insights represents a valuable approach for advancing therapeutic discovery. This study used Mendelian randomization (MR) to systematically screen druggable genes and prioritize genetic targets for delirium. Among 5883 druggable genes examined, we...

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PMID: 41905541
DOI: 10.1016/j.brainresbull.2026.111849

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POU5F1

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