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Article

Significance of genetic modifiers of hemoglobinopathies leading towards precision medicine.

Scientific reports - 22 Oct 2021

Hariharan Priya, Gorivale Manju, Sawant Pratibha, Mehta Pallavi, Nadkarni Anita

Abstract excerpt

Hemoglobinopathies though a monogenic disorder, show phenotypic variability. Hence, understanding the genetics underlying the heritable sub-phenotypes of hemoglobinopathies, specific to each population, would be prognostically useful and could inform personalized therapeutics. This study aimed to evaluate the role of genetic modifiers leading to higher HbF production with cumulative impact of the modifiers on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34686692
DOI: 10.1038/s41598-021-00169-x
PMCID: PMC8536722

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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