Article
Molecular genetics analysis of genes BCL11A, HBS1L-MYB, and HBG2 variants association in thalassemic children.
Personalized medicine - 1 Aug 2026
Lu Rongjian, Bashir Kashif, Tayyaba Manzoor Hafiza, Imran Ayesha, Kashif Muhammad, Tabasum Umbreen, Saqim Nadeem Iqra, Umar Muhammad, Alamin Amin A
Abstract excerpt
BACKGROUND: Association of the BCL11A (rs4671393), HBG2 (rs7482144), and HBG2HBS1L-MYB (rs28384513, rs9399137, and rs4895441) variants with susceptibility to thalassemia was observed. METHODOLOGY: Blood samples from 600 individuals, including 300 thalassemia patients and 300 controls, age- and gender-matched, were collected. DNA was extracted, followed by DNA Amplification. RESULTS: Results show that the...