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Article

Genetic exploration of the impact of CYP11A1 polymorphisms on the development of PCOS: evidence from a meta-analysis with trial sequential analysis.

Scientific reports - 3 Jun 2026

Miah Arafat, Datta Anamika, Shuvo Fojla Rabby, Barek Md Abdul, Islam Mohammad Safiqul

Abstract excerpt

Altering CYP11A1 expression due to polymorphisms can increase the likelihood of developing polycystic ovarian syndrome (PCOS). Several CYP11A1 polymorphisms have been extensively studied for their association with PCOS risk, but the findings have been inconsistent. To clarify this association, a meta-analysis was conducted to evaluate the relationship between various CYP11A1 variants and PCOS. A comprehensive...

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Share to Cholesterol Side-Chain Cleavage Enzyme
Share to Genetic Association Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 42236528
DOI: 10.1038/s41598-026-50710-z
PMCID: PMC13473682

Genes

CYP11A1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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