Article
Association Analysis of CYP11A1 Variants with Polycystic Ovary Syndrome: a Case-Control Study from North India.
Reproductive sciences (Thousand Oaks, Calif.) - 1 Oct 2021
Kaur Ratneev, Kaur Tajinder, Sudhir Neha, Kaur Anupam
Abstract excerpt
The most common multifactorial endocrine disorder in females of reproductive age is polycystic ovary syndrome (PCOS), affecting about 5-10% of females worldwide and 9.3% of females in India. Androgen excess in PCOS is caused as a result of defects in steroidogenesis genes. CYP11A1 is an imperative marker in the steroid synthesis pathway, and the altered expression of CYP11A1 has been reported to disrupt the...
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