European and Canadian derived risk prediction equations for atherosclerotic cardiovascular disease are valid in Australian patients with genetically confirmed familial hypercholesterolaemia.

Abstract excerpt

BACKGROUND AND AIMS: Familial hypercholesterolaemia (FH) is a co-dominantly inherited condition that leads to enhanced risk of atherosclerotic cardiovascular disease (ASCVD). We evaluated and compared the discriminatory ability of the SAFEHEART Risk Equation (SAFEHEART-RE), FH-Risk-Score (FHRS), and Combined-FH-Score (CFHS) in predicting incident ASCVD events among Australian patients with heterozygous FH (HeFH)....

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