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Article

Systematic identification of familial hypercholesterolaemia: An updated systematic review and meta-analysis.

Atherosclerosis - 1 Feb 2026

Daley Diandra, Ayoub Aya, Akyea Ralph K, L'Esperance Veline, Silva Luisa, Wierzbicki Anthony S, Williams Helen, Qureshi Nadeem, Molokhia Mariam

Abstract excerpt

BACKGROUND AND AIMS: Familial hypercholesterolaemia (FH) is an inherited lipid disorder characterised by raised LDL-C and increased risk of premature atherosclerotic cardiovascular disease. Despite effective treatments, FH remains substantially underdiagnosed. Electronic health records (EHRs) enable systematic case-finding, but evidence on their effectiveness remains limited. This review aimed to evaluate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41478251
DOI: 10.1016/j.atherosclerosis.2025.120625

Genes

FH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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Systematic identification of familial hypercholesterolaemia: An updated systematic review and meta-analysis.PMID 41478251Read ↗

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