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Article

Growth arrest of thoracic aortic aneurysms in aging Marfan mice.

American journal of physiology. Heart and circulatory physiology - 1 Jul 2026

Means Colin W, Mays Gavin, Yeung Nicola, Cavinato Cristina, Manning Edward P, Lam TuKiet T, Humphrey Jay D, Weiss Dar

Abstract excerpt

There remains a pressing need to identify pathological mechanisms that render a thoracic aortic aneurysm susceptible to continued enlargement, dissection, or rupture, yet additional insight can be gleaned by understanding compensatory mechanisms that limit disease progression and thereby stabilize a lesion. Our biomechanical data suggest that the ascending aorta within a common mouse model of Marfan syndrome,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42222959
DOI: 10.1152/ajpheart.00007.2026
PMCID: PMC13471068

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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