Article
Spring loading a pre-cleavage intermediate for hairpin telomere formation.
Nucleic acids research - 13 Jul 2015
Lucyshyn Danica, Huang Shu Hui, Kobryn Kerri
Abstract excerpt
The Borrelia telomere resolvase, ResT, forms the unusual hairpin telomeres of the linear Borrelia replicons in a process referred to as telomere resolution. Telomere resolution is a DNA cleavage and rejoining reaction that proceeds from a replicated telomere intermediate in a reaction with mechanistic similarities to that catalyzed by type IB topoisomerases. Previous reports have implicated the hairpin-binding...
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