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Article

Design and characterization of hyperactive mutants of the Agrobacterium tumefaciens telomere resolvase, TelA.

PloS one - 1 Jan 2024

Huang Shu Hui, Abrametz Kayla, McGrath Siobhan L, Kobryn Kerri

Abstract excerpt

Telomere resolvases are a family of DNA cleavage and rejoining enzymes that produce linear DNAs terminated by hairpin telomeres from replicated intermediates in bacteria that possess linear replicons. The telomere resolvase of Agrobacterium tumefaciens, TelA, has been examined at the structural and biochemical level. The N-terminal domain of TelA, while not required for telomere resolution, has been demonstrated...

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Identifiers

PMID: 39052566
DOI: 10.1371/journal.pone.0307590
PMCID: PMC11271964

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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