Article
Construction and characterization of a Borrelia burgdorferi strain with conditional expression of the essential telomere resolvase, ResT.
Journal of bacteriology - 1 Jul 2014
Bandy Nicholas J, Salman-Dilgimen Aydan, Chaconas George
Abstract excerpt
Borrelia species are unique in the bacterial world in possessing segmented genomes which sometimes contain over 20 genetic elements. Most elements are linear and contain covalently closed hairpin ends requiring a specialized process, telomere resolution, for their generation. Hairpin telomere resolution is mediated by the telomere resolvase, ResT. Although the process has been studied extensively in vitro, the...
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