Article
Burnt-Out MASLD Predicts Outcomes After Curative Resection for Hepatocellular Carcinoma.
Liver international : official journal of the International Association for the Study of the Liver - 1 Jul 2026
Watanabe Yukihiro, Aikawa Masayasu, Murase Yoshiki, Oba Takuya, Kageyama Yumiko, Takase Kenichiro, Watanabe Yuichiro, Ono Hiroaki, Okada Katsuya, Okamoto Kojun, Koyama Isamu
Abstract excerpt
BACKGROUND AND AIMS: Hepatic steatosis often diminishes as metabolic dysfunction-associated steatotic liver disease (MASLD) progresses, leading to a so-called 'burnt-out' state. Whether this phenotype simply reflects advanced liver injury or represents a biologically distinct condition with prognostic relevance after hepatocellular carcinoma (HCC) development remains unclear. We evaluated the clinical...
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