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Emergence and Evolution of Triple Reassortant Highly Pathogenic Avian Influenza A(H5N1) Virus, Argentina, 2025.

Viruses - 30 Apr 2026

Benedetti Estefania, Artuso Maria Carolina, Byrne Alex, Garibotto Maria de Belen, Avaro Martín, Piccini Luana, Chamorro Ariana, Sciorra Marcelo, Marchione Vanina, Russo Mara, Dattero Maria Elena, Machicado Erika Macias, Galiano Monica, Lewis Nicola, Pontoriero Andrea

Abstract excerpt

The H5N1 subtype of highly pathogenic avian influenza (HPAI) poses a major zoonotic threat due to its high fatality rate and capacity for cross species transmission. In early 2025, Argentina detected a novel triple reassortant A(H5N1) virus in Chaco Province, combining Eurasian, North American, and South American lineage segments. Genomic analyses of subsequent outbreaks in Buenos Aires and Entre Ríos confirmed...

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Identifiers

PMID: 42198727
DOI: 10.3390/v18050525
PMCID: PMC13211697

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