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Reassortant High Pathogenicity Avian Influenza A(H5N1) Viruses During the Reemergence in Uruguay Suggest Increasing Genetic Diversity in South America.

Viruses - 14 May 2026

Marandino Ana, Tomás Gonzalo, Panzera Yanina, Uriarte Valeria, Russi Virginia, Pérez Ramiro, Bassetti Lucía, Negro Raúl, Rodríguez Sirley, Pérez Ruben

Abstract excerpt

Highly pathogenic avian influenza (HPAI) H5N1 viruses of the goose/Guangdong (Gs/GD) lineage have driven a global panzootic since 2020, with clade 2.3.4.4b establishing sustained transmission in wild birds. In South America, early outbreaks were largely associated with the North American-derived B3.2 genotype, which showed limited diversification after its introduction. Here, we report the genomic...

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Identifiers

PMID: 42198761
DOI: 10.3390/v18050558
PMCID: PMC13211659

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