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Article

The Variant rs2706682 at PITPNC1, Which Enhances Vehicular Secretion, Associated With Systemic Lupus Erythematosus Susceptibility in Chinese Populations.

International journal of immunogenetics - 1 Aug 2026

Duan Ruiying, Qi Yuanyuan, Zhang Yangming, Zhu Tengyu, Liu Chen, Hu Huimiao, Guo Jia, Zhao ZhanZheng, Yu Dahai

Abstract excerpt

Systemic lupus erythematosus (SLE) is a multifactorial autoimmune disease in which genetic and environmental factors play important role in SLE pathogenesis. Recently, cytoplasmic phosphatidylinositol transfer protein 1 (PITPNC1) was reported to be capable of enhancing vesicular secretion, which was correlated with autoimmune disorders contributing to SLE. Here, we aimed to explore the genetic association between...

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Identifiers

PMID: 42186263
DOI: 10.1111/iji.70056
PMCID: PMC13352099

Genes

PITPNC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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