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Article

Assessment of the association between TNIP1 polymorphism with clinical features and risk of systemic lupus erythematosus.

Lupus - 1 Jul 2022

Azhdari Sara, Saghi Mostafa, Alani Behrang, Zare Rafie Maryam, Kenarangi Taiebe, Nasrollahzadeh Sabet Mehrdad, Pakzad Bahram, Ghorashi Tahereh, Gholami Milad, Soosanabadi Mohsen

Abstract excerpt

OBJECTIVE: Over the past decades, TNIP1 has been identified as a strong risk locus in multiple genome-wide association studies (GWAS), spanning multiple populations and various autoimmune diseases. TNIP1 is a polyubiquitin-binding protein that works as a physiological inhibitor of NF-κB and maintains immune homeostasis. Some studies have confirmed that TNIP1 is downregulated in autoimmune diseases such as...

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PMID: 35475371
DOI: 10.1177/09612033221094706

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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