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Article

Genetic profiling of sulfadoxine-pyrimethamine resistance markers in Indian Plasmodium falciparum field isolates.

Future microbiology - 1 Apr 2026

Narang Geetika, Jakhan Jahnvi, Gupta Divyanshi, Singh Vineeta

Abstract excerpt

AIMS: Sulfadoxine-pyrimethamine (SP) is widely used as a partner drug in artemisinin combination therapy for Plasmodium falciparum malaria in India, except in the North-Eastern states. Drug resistance arises through mutations in Pfdhfr and Pfdhps, compromising treatment efficacy. The study investigated geographic distribution, temporal trends and molecular evolution of SP resistance markers in P. falciparum field...

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Identifiers

PMID: 42178979
DOI: 10.1080/17460913.2026.2677416
PMCID: PMC13228975

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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