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Article

Inflammatory factors and hypertensive nephropathy: A bidirectional 2-sample Mendelian randomization study.

Medicine - 22 May 2026

Yang Yu, Xue Jianfeng, Wang Lei, Tao Lei, Tian Lu

Abstract excerpt

Hypertensive nephropathy (HTN) is a major public health concern worldwide. This study aims to investigate the potential causal relationships between inflammatory factors and HTN, as well as to identify possible underlying biological pathways. Using genome-wide association study data from large publicly available population cohorts, we applied a bidirectional 2-sample Mendelian randomization approach to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42175402
DOI: 10.1097/MD.0000000000048842
PMCID: PMC13201012

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