Bifidobacterium breve Promotes the Pathogenesis of IBS by Downregulating the Expression of Ferroptosis-Related Molecule ERBB1: A Mendelian Randomization Mediation Analysis.

Abstract excerpt

Objective: Although gut microbiota dysbiosis has been associated with irritable bowel syndrome (IBS), the specific roles of individual bacterial strains in the pathogenesis of IBS remain incompletely elucidated. Additionally, whether these bacterial strains exert their effects through the ferroptosis pathway remains unclear. Therefore, this study is aimed at investigating the impact of ferroptosis-related...

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