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Article

Investigating the causal relationship of gut microbiota with GERD and BE: a bidirectional mendelian randomization.

BMC genomics - 14 May 2024

Liu Yuan, Yu Jiali, Yang Yuxiao, Han Bingyu, Wang Qiao, Du Shiyu

Abstract excerpt

BACKGROUND: Gut microbiota(GM) have been proven associated with lots of gastrointestinal diseases, but its causal relationship with Gastroesophageal reflux disease(GERD) and Barrett's esophagus(BE) hasn't been explored. We aimed to uncover the causal relation between GM and GERD/BE and potential mediators by utilizing Mendelian Randomization(MR) analysis. METHODS: Summary statistics of GM(comprising 301 bacteria...

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Identifiers

PMID: 38745153
DOI: 10.1186/s12864-024-10377-0
PMCID: PMC11092028

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