Article
Assessing the relationship between gut microbiota and irritable bowel syndrome: a two-sample Mendelian randomization analysis.
BMC gastroenterology - 12 May 2023
Liu Bin, Ye Ding, Yang Hong, Song Jie, Sun Xiaohui, He Zhixing, Mao Yingying, Hao Guifeng
Abstract excerpt
BACKGROUND: Growing evidence has suggested that gut microbiota is closely related to the risk of irritable bowel syndrome (IBS), but whether there is a causal effect remains unknown. We adopted a Mendelian randomization (MR) approach to evaluate the potential causal relationships between gut microbiota and the risk of IBS. METHODS: Genetic instrumental variables for gut microbiota were identified from a...
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