Article
The mediating effect of circulating inflammatory proteins on the relationship between gut microbiota and FD: a bidirectional Mendelian randomization study.
Scientific reports - 11 Oct 2024
Li Li, Fu Minhan, Chen Feiyi, Ji Huijie, Zhou Guowei, Chen Lu, Geng Hao, Guo Jing, Pei Lixia, Sun Jianhua
Abstract excerpt
Functional dyspepsia (FD) is known to be influenced by gut microbiota (GM) and circulating inflammatory proteins (CIPs), however, the causal relationship between GM, CIPs and FD haven't been investigated. This study employed two-sample Mendelian Randomization (TSMR) to investigate their associations using data from Genome-Wide Association Studies (GWAS). In this study, Inverse-variance weighted (IVW) method was...
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