Article
Genomic findings in schizophrenia and their implications.
Molecular psychiatry - 1 Sept 2023
Owen Michael J, Legge Sophie E, Rees Elliott, Walters James T R, O'Donovan Michael C
Abstract excerpt
There has been substantial progress in understanding the genetics of schizophrenia over the past 15 years. This has revealed a highly polygenic condition with the majority of the currently explained heritability coming from common alleles of small effect but with additional contributions from rare copy number and coding variants. Many specific genes and loci have been implicated that provide a firm basis upon...
Topics
- Humans
- Child
- Schizophrenia
- Bipolar Disorder
- Genome
- Genomics
- Emotions
- Genetic Predisposition to Disease
- Genome-Wide Association Study