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Article

The synergistic action of reduced membrane permeability and antibiotic sequestration as a novel mechanism for carbapenem resistance in Campylobacter.

mBio - 10 Jun 2026

Chen Xinggui, Zhou Yulian, Zhou Quan, He Min, Zhao Mengyu, Dai Suchuan, Li Jinpeng, Hou Chengyao, Tao Weilai, Yang Xinyi, Lan Shiying, Yang Xin, Lei Changwei, Zhang Anyun, Wang Hongning, Tang Yizhi

Abstract excerpt

Carbapenems are last-resort antibiotics against gram-negative pathogens, including multidrug-resistant Campylobacter. However, carbapenem-resistant Campylobacter strains are emerging and have been isolated in patients treated with carbapenems. This emerging resistance mechanism may be underpinned by multiple genetic determinants, yet it has not been systematically characterized or elucidated until now. In this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42159377
DOI: 10.1128/mbio.00364-26
PMCID: PMC13251398

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