The power of genetics in decoding Sjögren's disease: current status and future development.

Abstract excerpt

Sjögren's disease (SjD) is the second most common systemic autoimmune disease in the United States. SjD patients are predominantly women 30-50 years of age and exhibit heterogeneous clinical manifestations, including symptoms of extensive dryness, chronic fatigue, and joint pain, and various major organ involvement. Late onset, clinical heterogeneity, and limited mechanistic understanding of its etiology...

Topics

• Humans
• Sjogren's Syndrome
• Genetic Predisposition to Disease
• Genome-Wide Association Study
• Animals