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Integrative analysis of genomic and epigenetic regulation of endometrial cancer.

Aging - 15 May 2020

Zhong Qihang, Fan Junpeng, Chu Honglei, Pang Mujia, Li Junsheng, Fan Yong, Liu Ping, Wu Congying, Qiao Jie, Li Rong, Hang Jing

Abstract excerpt

Endometrial carcinomas (EC) are characterized by high DNA copy numbers and DNA methylation aberrations. In this study, we sought to comprehensively explore the effect of these two factors on development and progression of EC by analyzing integrated genomic and epigenetic analysis to. We found high DNA copy number and DNA methylation abnormalities in EC, with 6308 copy-number variation genes (CNV-G) and 4376...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32412912
DOI: 10.18632/aging.103202
PMCID: PMC7288931

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