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Clinical, biological and genome-wide comparison of carbapenem-resistant Klebsiella pneumoniae with susceptibility transformation to polymyxin B during therapy

7 Jul 2023

Abstract excerpt

OBJECTIVES: The emergence of carbapenem-resistant Klebsiella pneumoniae (CRKP) is a major clinical concern, and polymyxin B (PMB) is a 'last resort' antibiotic for its treatment. Understanding the effects of drug susceptibility transformation in CRKP-infected patients undergoing PMB treatment would be beneficial to optimize PMB treatment strategies. METHODS: We retrospectively collected data from patients...

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PMID: 37423426
DOI: 10.1016/j.cmi.2023.06.029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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