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Article

Increased risk of the onset and exacerbation of COPD in metabolic syndrome patients: A 2-sample Mendelian randomization study.

Medicine - 15 May 2026

Xu Ling, Sun Jiantong, Yang Lan, Chen Yaxin, Wang Haoyu, Li Lei

Abstract excerpt

This study aimed to assess the genetic associations of metabolic syndrome (MetS) and its components with the onset and exacerbation of chronic obstructive pulmonary disease (COPD), including respiratory failure and pneumonia. Summary statistics were sourced from publicly available genome-wide association studies. Genetic instruments were selected at genome-wide significance and linkage disequilibrium clumped via...

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Identifiers

PMID: 42152420
DOI: 10.1097/MD.0000000000048701
PMCID: PMC13183019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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