Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Genetic association and potential mediators between metabolic syndrome and chronic obstructive pulmonary disease: A Mendelian randomization study.

Medicine - 13 Mar 2026

Zhang Yunlong, Zhang Qun

Abstract excerpt

Chronic obstructive pulmonary disease (COPD) is a common and serious health issue. Epidemiological studies indicate a significant link between metabolic syndrome (MetS) and its components with the risk of developing COPD. However, observational studies are prone to confounding and reverse causation, so the causal relationship and underlying mechanisms between MetS and COPD remain unclear. This study used 2-sample...

Topics

Join the communities discussing this publication.

Body Mass Index
Genome-Wide Association Study
Hypertension
Mendelian Randomization Analysis
Metabolic Syndrome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pulmonary Disease, Chronic Obstructive

Waist Circumference

Source

Open in PubMed Open full text

Identifiers

PMID: 41824853
DOI: 10.1097/MD.0000000000048031
PMCID: PMC12991744

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic association and potential mediators between metabolic syndrome and chronic obstructive pulmonary disease: A Mendelian randomization study.PMID 41824853Read ↗

Increased risk of the onset and exacerbation of COPD in metabolic syndrome patients: A 2-sample Mendelian randomization study.Semantic proximity Read ↗

Relationship between tobacco smoking and metabolic syndrome: a Mendelian randomization analysisSemantic proximity Read ↗

Exploring the causal relationship between asthma in the metabolic syndrome: a Mendelian randomization study.Semantic proximity Read ↗

The association between metabolic syndrome and lung cancer risk: a Mendelian randomization study.Semantic proximity Read ↗

Causal Relationships Between Blood Lipid Levels and Chronic Obstructive Pulmonary Disease: A Mendelian Randomization AnalysisSemantic proximity Read ↗

COPD and T2DM: a Mendelian randomization studySemantic proximity Read ↗

Association of air pollution, lifestyle factors, and metabolic syndrome: a Mendelian randomization studySemantic proximity Read ↗

Metabolic syndrome, genetic susceptibility, and risk of chronic obstructive pulmonary disease: The UK Biobank Study.Semantic proximity Read ↗

Thyroid Function and Metabolic Syndrome: A Two-Sample Bidirectional Mendelian Randomization StudySemantic proximity Read ↗

Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study.Semantic proximity Read ↗

Nicotine Metabolism and Chronic Obstructive Pulmonary Disease: Mendelian Randomization and Phenotypic Characterization Analysis.Semantic proximity Read ↗

Causal associations of obstructive sleep apnea with Chronic Respiratory Diseases: a Mendelian Randomization study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.