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The association between metabolic syndrome and lung cancer risk: a Mendelian randomization study.

Scientific reports - 18 Nov 2024

Wei Zhicheng, Hu Yunyun, Zuo Fang, Wen Xiushu, Wu Desheng, Sun Xiaodong, Liu Conghai

Abstract excerpt

Metabolic syndrome (MetS) is closely linked to cancer development, with emerging evidence suggesting its association with pulmonary carcinoma. However, causal relationships remain unclear due to observational study limitations. Employing Mendelian randomization, we investigated the causal link between MetS and lung cancer (LC) susceptibility. The data utilized in this study were obtained from the publicly...

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Genetic Predisposition to Disease
Lung Neoplasms
Mendelian Randomization Analysis
Metabolic Syndrome
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Small Cell Lung Carcinoma

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Identifiers

PMID: 39558018
DOI: 10.1038/s41598-024-79260-y
PMCID: PMC11574301

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