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Article

Re-Evaluating the Relationship Between Insulin Resistance and Chronic Obstructive Pulmonary Disease: Evidence from NHANES and Mendelian Randomization.

International journal of chronic obstructive pulmonary disease - 1 Jan 2026

Jiang Na, Jin Qian, Xu Weihua, Huang Feihua

Abstract excerpt

Background and Purpose: Observational studies suggest an association between insulin resistance (IR) and chronic obstructive pulmonary disease (COPD), but this link is susceptible to confounding and reverse causality. This study integrated cross-sectional analysis with Mendelian Randomization (MR) to systematically evaluate their potential causal relationship. Methods: Using NHANES data, we employed complex...

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Identifiers

PMID: 42040645
DOI: 10.2147/COPD.S587160
PMCID: PMC13108481

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