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Article

Integrated genomics and transcriptomics reveal key events in pancreatic neuroendocrine neoplasm.

BMC biology - 19 May 2026

Guo Shiwei, Shi Xiaohan, Yin Xiaoyi, Gao Suizhi, Li Bo, Wang Huan, Li Yikai, Wang Beilei, Xu Xiongfei, Zheng Kailian, Song Bin, Jing Wei, Song Chengli, Jin Gang

Abstract excerpt

BACKGROUND: Pancreatic neuroendocrine neoplasm (PanNEN) represents the second most common epithelial neoplasm of the pancreas, characterized by remarkable heterogeneity among its subtypes. This study aimed to comprehensively characterize the molecular landscape of PanNENs and identify key features associated with tumor progression and therapeutic implications. RESULTS: We performed an integrated molecular...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42152075
DOI: 10.1186/s12915-026-02637-0
PMCID: PMC13352993

Genes

KRAS
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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