Article
Application of multiomics sequencing and advances in the molecular mechanisms of pancreatic neuroendocrine neoplasms.
Cancer letters - 28 Feb 2021
Jiang Rui, Hong Xiafei, Zhao Yupei, Wu Wenming
Abstract excerpt
The incidence of pancreatic neuroendocrine neoplasms (PanNENs) has gradually increased. PanNENs comprise two subtypes with different clinical manifestations and molecular mechanisms: functional PanNENs and nonfunctional PanNENs. Excessive hormones and tumor progression severely affect the quality of life of patients or are even life threatening. However, the molecular mechanisms of hormone secretion and tumor...
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