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Article

Identification of a Rejection Signature and Distinct Inflammatory Alveolar Macrophage Populations Post-lung Transplantation.

Transplantation - 1 Jul 2026

Barbosa Vera M, Hu Guangan, Vaidyanathan Shruti, Akbariromani Hanieh, Justice Samuel, Madsen Jens, Sheikh Adil, El-Chemaly Souheil Y, Sholl Lynette Marie, Coppolino Anthony, Mallidi Hari R, Elias Kevin M, Roghanian Ali, Chen Jianzhu, Frendl Gyorgy

Abstract excerpt

BACKGROUND: The long-term outcome of lung transplantation remains inferior to that of other solid organ transplants, primarily due to rejection/infection. This pilot study investigates longitudinal changes in the bronchoalveolar lavage (BAL) leukocyte transcriptomes and phenotypes, and their impact on clinical outcomes. METHODS: BAL samples were collected at baseline and 1-12 mo posttransplantation. Leukocyte...

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Share to Bronchoalveolar Lavage Fluid
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 42150128
DOI: 10.1097/TP.0000000000005742

Genes

CD163
CD80
CD86

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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