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Article

CFD+CD14+ monocytes: potential pathogenic subset in myasthenia gravis uncovered by multi-omics integration and machine learning analysis.

Frontiers in immunology - 1 Jan 2026

Li Shuang, Zhang Yifan, Hou Chenlu, Chang Ting

Abstract excerpt

Background: Transcriptome-wide association study (TWAS) contributes to discovering novel susceptibility genes related to diseases. Single-cell RNA sequencing (scRNA-seq) has been extensively applied to characterize cellular heterogeneity in various biological and pathological conditions. However, few studies have integrated TWAS and scRNA-seq to decode the pathogenesis of myasthenia gravis (MG) at cellular...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42148089
DOI: 10.3389/fimmu.2026.1813107
PMCID: PMC13176296

Genes

CFD
CD14
CHPT1
EHMT1
FKBP15
KLC1
SCPEP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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