Article
Identifying a polymorphic 'switch' that influences miRNAs' regulation of a myasthenia gravis risk pathway.
PloS one - 1 Jan 2014
Yang Lili, Wang Jianjian, Sun Xuesong, Cao Yuze, Ning Shangwei, Zhang Huixue, Chen Lixia, Li Ronghong, Tian Qinghua, Wang Lihua, Wang Weizhi, Li Xia
Abstract excerpt
The significant roles of genetic variants in myasthenia gravis (MG) pathogenesis have been demonstrated in many studies, and recently it has been revealed that aberrant level/regulation of microRNAs (miRNAs) might contribute to the initiation and progression of MG. However, the dysfunction of miRNA associated with single nucleotide polymorphisms (miRSNPs) has not been well investigated in MG. In this study, we...
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