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Article

Association between night shift work, genetic risk, and chronic kidney disease: a prospective cohort study based on the UK Biobank.

Frontiers in public health - 1 Jan 2026

Xu Qianchun, Fan Jiayao, Chen Zhiyi, Lv Duo, Zhou Dan, Shou Zhangfei, Xie Xishao

Abstract excerpt

Objective: To investigate the association between night shift work and chronic kidney disease (CKD) risk and evaluate the interacting role of genetic susceptibility. Methods: This prospective cohort study included 252,425 participants from the UK Biobank for current night shift analysis and 67,097 for lifetime exposure. Cox proportional hazards models assessed the relationship between various shift patterns and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 42145513
DOI: 10.3389/fpubh.2026.1772746
PMCID: PMC13171536

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

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