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Longitudinal Study of Frailty Phenotype in Relation to Chronic Kidney Disease Incidence.

Journal of cachexia, sarcopenia and muscle - 1 Jun 2026

Ruan Yong-Xiang, Guo Da-Chuan, Liu Wen-Hao, Ou Jia-Man, Guo Qi, Gao Jing-Wei, Cai Yang-Wei, Wu Mao-Xiong, Liang Xiao-Tian, Cai Jie-Wen, Liu Pin-Ming, Wang Jing-Feng, Zhang Hai-Feng, Chen Yang-Xin

Abstract excerpt

BACKGROUND: The longitudinal relationship between frailty phenotype and CKD development, and the modifying role of genetic CKD risk in this association, remains unclear. Research on simple, noninvasive and quantifiable CKD prediction models incorporating frailty is limited. METHODS: We analysed 214 502 CKD-free participants from the UK Biobank cohort. Frailty was assessed using a modified phenotype with five...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42014030
DOI: 10.1002/jcsm.70287
PMCID: PMC13099170

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