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Article

Metabolite-Based Endotypes of Asthma Reveal Distinct Clinical Characteristics and Immune Cell Signatures.

Allergy - 1 Sept 2026

Pyung Young Jin, Kang Noeul, Chun Jihyun, Yu Keesun, Park Da-Jeong, Lee Do Yup, Kim Deog Kyeom, Lee Hyun Woo, Yun Cheol-Heui

Abstract excerpt

BACKGROUND: Asthma control is commonly defined by symptom burden and recent exacerbation history. However, symptom-based clinical stability does not necessarily reflect biological quiescence, and heterogeneity in lung function and airway structure may persist despite apparent clinical control. This study aimed to determine whether blood-based metabolomic profiling can discriminate biologically distinct subgroups...

Read the complete abstract on PubMed

Topics

Humans
Asthma
Female
Metabolomics
Male
Metabolome
Adult

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Biomarkers

Middle Aged

Respiratory Function Tests

Phenotype

Prospective Studies

Source

Open in PubMed Open full text

Identifiers

PMID: 42130017
DOI: 10.1111/all.70385
PMCID: PMC13569713

Genes

C2
C3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

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